4.9 · Trusted by 10,600+ dog owners
Shield-K3V | Immune & Gut
Daily support for the gut, skin, and immune system that keep them comfortable. For itchy skin, sensitive stomachs, and digestion that's reliably steady.
- Supports healthy digestion and gut lining
- Supports a balanced immune response
- Helps maintain healthy skin and coat
How to use
Draw one dropper and place it directly on your dog's tongue or over food, once a day. Follow the serving directions on your bottle. Keep refrigerated.
What's inside
An immune peptide fraction paired with purposeful co-nutrients for the gut barrier and the gut-skin connection. Every ingredient and its amount is on the label. Nothing hidden in a proprietary blend.
Testing and quality
Every lot is third-party tested for purity, potency and safety before it ships. Your bottle's batch code matches its certificate.
Shipping and returns
Shipped cold in insulated packaging. Free cold shipping on subscriptions. Not the right fit? Our 30-day money-back guarantee has you covered.
Batch Tested
Third-party verified
Made In USA
Formulated and bottled
Cold-Shipped
Arrives fresh, ready to use
For this dog
The signs are visible. The cause usually isn't.
- The paw licking that won't stop.
- The scratching that gets worse in certain seasons.
- The stomach that never quite settles.
Gut and skin issues are among the most common reasons owners look for a supplement. They're also among the hardest to address, because the connection between them, the gut barrier and the immune response it governs, is rarely explained on the label. Shield is built for that dog: daily gut and immune support that starts where most of the problem originates.
Not a quick fix. Not a steroid.
The ingredients in Shield support the gut barrier where most of the immune system does its work.
What's in it
Every ingredient listed.
Every amount disclosed.
Every active below is in the formula, with the amount per daily serving. Nothing here that is not on the label.
-
Primary active
Immune peptide fraction
[amount] mg
Targeted peptide sequences support the gut epithelial barrier, the lining where most of the immune system's training and response happen. A stronger barrier supports calmer, more consistent tolerance.
-
[Co-nutrient 2, e.g. L-Glutamine]
[amount] mg
Placeholder until the formula is confirmed. Replace with what it does and why it is included.
-
[Co-nutrient 3, e.g. Beta-1,3/1,6-glucans]
[amount] mg
Placeholder until the formula is confirmed. Replace with what it does and why it is included.
-
[Co-nutrient 4, e.g. EPA/DHA or Omega-3s]
[amount] mg
Placeholder until the formula is confirmed. Replace with what it does and why it is included.
Exact names and amounts on the label. Nothing hidden in a proprietary blend.
How it works
The gut wall is where the immune system lives.
Most dogs with itchy skin or sensitive stomachs don't have a skin problem or a food problem in isolation. They have a gut barrier problem. The gut lining is where the immune system does most of its work: telling normal from threat, calibrating tolerance, regulating the inflammatory response.
Shield pairs immune peptides that support the gut barrier with nutrients that support balanced immune activity and the gut-skin connection. It addresses the root, not just the symptom.
-
The barrier
Supports the gut lining
The immune peptide fraction supports the gut epithelial barrier, where much of the immune system is trained.
-
The balance
Supports a calmer response
The co-nutrients support balanced immune activity and the gut-skin connection behind coat and comfort.
-
The delivery
Starts on the tongue
Delivered as a cold-processed tincture for mucosal uptake from the first drop. Uptake begins before digestion starts.
Why a tincture, not a chew
| Feature | Typical allergy chew | Shield |
|---|---|---|
| Actives | Single ingredient focus | Immune peptide fraction plus co-nutrients |
| Approach | Targets the symptom | Supports the gut barrier |
| Processing | Heat-extruded | Cold-processed |
| Absorption | After digestion | Starts on the tongue |
Consistency matters
Give it 3 to 5 weeks of daily use. Immune support takes time: the system is being supported, not suppressed.
The ritual
One dropper. On the tongue.
Every day.
Thirty seconds a day, straight from the fridge door. No pill pockets, no crushed tablets hidden in dinner, no negotiation.
-
Keep it cold
PupPepz lives in your refrigerator, next to the things you keep fresh on purpose. Cold storage protects peptide integrity for the full 30-day supply.
-
Draw one dropper
1 mL daily for dogs up to 50 lb, 2 mL for 50 lb and over. The graduated dropper is precise to the line, every time.
-
Drop on the tongue
Mild, savory-neutral taste dogs accept readily. Absorption starts before the bowl is even down.
FAQ
Questions, answered.
Everything owners ask us before their first bottle.
What are peptides, and are they safe for dogs?
Peptides are short chains of amino acids, the building blocks of protein. Your dog's body already makes and uses them. PupPepz provides peptide fractions and co-nutrients as a supplement to your dog's normal diet. Always check with your vet before starting any supplement, especially if your dog has a medical condition or takes medication.
How much do I give my dog?
1 mL daily for dogs up to 50 lb, 2 mL daily for dogs over 50 lb. Directly on the tongue or over food.
Why does it need to be refrigerated?
Cold storage protects peptide integrity. It's the same reason the tincture is cold-processed and cold-shipped.
Can Shield be used alongside other PupPepz formulas?
Yes. Shield pairs well with Motion for dogs with multiple concerns, and with Longevity for older dogs whose gut and immune function both benefit from daily support.
How long before the itching or stomach issues improve?
Give it 3 to 5 weeks of daily use. Dogs with severe sensitivities may take longer, as the gut barrier rebuilds gradually. Every dog is different.
Is Shield a replacement for an elimination diet or allergy testing?
No. If your dog has suspected food allergies or environmental sensitivities, talk to your veterinarian. Shield supports the gut barrier and immune system. It is not a diagnostic tool or a substitute for identifying root causes.
Is this safe for long-term daily use?
Shield is designed for ongoing daily use as supportive nutrition. As with any supplement, check with your vet if your dog has a medical condition or takes medication.
Can I pause or cancel my subscription?
Anytime, from your account. No calls, no forms.
Our Peptides
Every formula answers
a need you can see.
-
Motion-157 | Joints & Mobility
Joints & mobility · BPC-157
For stiff mornings, slow stairs, and the walks they still love.
$59.99 one-time · $49.99 / month
-
Shield-K3V | Immune & Gut
Gut & immune · KPV
For itchy skin, sensitive stomachs, and digestion that's reliably steady.
$59.99 one-time · $49.99 / month
-
NAD+ | Cellular Longevity
Cellular vitality · NAD+
For the years ahead. Support for cellular energy and antioxidant balance.
$59.99 one-time · $49.99 / month
-
Calm-S7 | Calming Support
SKIN & COAT · GHK-CU
For dull coats, dry skin, and the shine you remember.
$59.99 one-time · $49.99 / month
-
Glow-Cu | Skin & Coat
CALM & BALANCE · SELANK
For thunderstorms, car rides, and the hours they spend home alone.
$59.99 one-time · $49.99 / month
-
Smile-157 | Teeth & Gums
TEETH & GUMS · BPC-157
For tender gums, tough chews, and a smile that stays comfortable.
$59.99 one-time · $49.99 / month
Give them the years. Start with one dropper.
Save 15% on every subscription. Skip, pause or cancel anytime.






